Betahistine HCL 16 mg– Betahistine is an antivertigo drug, extensively used for treating vertigo associated with Ménière’s disease, it is the type of health condition which is a condition caused by the pressure of excess fluid in the inner ear. Some of the major symptoms of having Ménière’s are vertigo, tinnitus, hearing loss and nausea. Dosage. It is also commonly used for patients with balance disorders. Patients with hypersensitivity are most likely to consume betahistine dihydrochloride or any component of the tablet on a prescription basis. Use in patients with phaeochromocytoma.
Betahistine HCL stands for Betahistine dihydrochloride, also called histamine analog. This medicine works by improving blood flow in the inner ear, which prevent the pressure to build up. This type of pressure cause vertigo (dizziness), tinnitus (ringing in the ears) and hearing loss suffered. Such medicines are very effective in treating such a health issue.
COMPOSITION OF THE BETAHISTINE DIHYDROCHLORIDE 16mg TABLETS
Each tablet contains 16mg betahistine dihydrochloride with the following excipients:
- Povidone K90
- Microcrystalline cellulose
- Lactose monohydrate
- Colloidal anhydrous silica
- Stearic acid
- Certain measures are to be kept in mind before prescribing these tablets. Those measures are:
- Patients suffering from porphyria aren’t advised to take Betahistine dihydrochloride tablets.
- It should be administered with caution to patients with bronchial asthma (due to clinical intolerance) or a history of peptic ulcer.
- These tablets are not recommended for use in children.
- Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.
SPECIFICATION USAGE OF THE TABLETS FOR CLINICAL PARTICULARS
- Pregnancy: There are no adequate data from the use of betahistine in pregnant women. Studies done on animals did not reach in a conclusion as effects on pregnancy, embryonal/foetal development, parturition, and postnatal development were insufficient. The potential risk for humans is unknown. As a precautionary measure, it is advised to avoid the use of betahistine during pregnancy.
- Lactation: Researchers aren’t able to find whether betahistine is excreted in human milk. But instead, it is excreted in rat milk. The effects post-partum in animal studies were limited to very high doses. Before prescribing the drug to the mother, she should be weighed resistant to the benefits of nursing and the potential risks for the child.
- Fertility: No changes were recorded in the fertility of the rats.It’s effect on the fertility of humans is yet to be found out.
Effects on ability to drive and use machines: Vertigo, tinnitus and hearing loss associated with Ménière’s syndrome can negatively affect the ability to drive and use machines.Betahistine had no or negligible effects that were noted in the clinical studies that are specifically designed to investigate the ability to drive and use machines.
UNDESIRABLE EFFECTS OF THE TABLETS
The following undesirable effects have been experienced with the below indicated frequencies in betahistine hydrochloride-treated patients in placebo-controlled clinical trials (very common (≥ 1/10); very common (_1/10); common (_1/100 to <1/10); uncommon (≥ /1,000 to < 1/100); rare (≥ /10,000 to < 1/1,000); very rare (<1/10,000))
- Gastrointestinal disorders: Undesirable effects caused by this are nausea and dyspepsia
- Nervous systems disorders: people might experience headache.
- Immune systems disorders: Hypersensitivity reactions, e.g. anaphylaxis have been reported.
- Gastrointestinal disorders: Mild gastric complaints (e.g. vomiting, gastrointestinal pain, abdominal distension and bloating) have been observed. Lowering down the dose or by taking the dose during meals can help to reduce these complications.
- Skin and subcutaneous tissue disorders: Cutaneous and subcutaneous hypersensitivity reactions have been reported in particular angioneuroticedema, urticaria, rash and pruritus.
PHARMACEUTICAL FEATURES OF BETAHISTINE DIHYDROCHLORIDE 16mg TABLETS
Certain features are to be kept in mind before dealing in these tablets. These features are:
- Shelf-life: This drug life is effective for a period of 3 years
- Special precautions for storage: Do not store above 25° C. Store in the original package. Keep container in the outer carton.
- Nature and contents of container: Blister strips consisting of 250 µm transparent PVC, a 60 g/m2 PVDC layer and 20µm hard temper aluminum foil, contained in a carton.
- Pack sizes: 60, 84, 90, 100 and 120 tablets.
- Special precautions for disposal and other handling: Not applicable.
What is Ménière’s Disease?
Ménière’s disease (MD) is a disorder of the inner ear that is characterized by episodes of feeling like the world is spinning (vertigo i.e. A sudden internal or external spinning sensation, often triggered by moving your head too quickly.) It also can cause ringing in your ear (tinnitus), hearing loss that comes and goes, and a feeling of fullness or pressure in your ear. Usually, only one ear is affected. The hearing loss eventually can be permanent.
Symptoms: Ménière’s is characterized by repetitive episodes of vertigo, hearing loss and tinnitus; it may be accompanied by a headache and a feeling of fullness in the hearing. Few symptoms of this disease are related to irregular reactions of the autonomic nervous system. People can also experience sudden falls unconsciously, also known as drop attacks.
Treatments: Till now, there is no known cure for this disease. Attacks are often treated with medications to help with nausea and anxiety. Few measures that can be taken to prevent attacks are overall poorly supported by the evidence.
- Diet including low salt, diuretics, and corticosteroids should be preferred.
- Physical therapy may help with balance and counseling may help with anxiety.
- Other measures like surgery may include risk.
- The use of tympanostomy tubes, while popular, is not supported.
NOTE: The overdose of any medicine can be harmful to your health. Consumption of any medicine without prescription can be dangerous.